glp-1 from canada approves first generic drug in G7 GLP-1 Drops, Advanced Shaping Body

For context: Novo Nordisk's FDA-approved drug semaglutide for weight loss, Wegovy, is also approved to reduce cardiovascular risks and to treat the fatty liver disease called metabolic-associated steatohepatitis (MASH)

The binding of the DPP4 S2-extensive subsite of some inhibitors also guarantees a high specificity toward DPP4 since other close-related peptidases like DPP8, DPP9, and FAP lack this subsite

[1] Losing muscle alongside fat matters because muscle is metabolically active tissue

On the other hand, in contrast to those enrolled in clinical trials, patients seen in routine clinical practice are allowed to switch between drugs within the same drug class, which could lower rates of treatment discontinuation

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