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The curing and processing also avoid chemical additives that commercial tobaccos may include

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Enrichment of AHR signaling pathway, glutathione biosynthesis, NRF2-mediated oxidative stress response, superoxide radicals degradation, xenobiotic metabolism signaling following transcriptomic analysis in bro-ALI and/ or alv-ALI in our exposure experiments are consistent with the CC-smoke associated oxidative stress and inflammatory response 43, 58

Unlike the dual components of a spliff, a joint remains pure in its dedication to just one ingredient: cannabis