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[DOI] [PubMed] [Google Scholar] 89.Rahman I., Macnee W

Emerging evidence suggests potential contributors, including nicotine toxicity, chronic exposure-induced neuroadaptations, and the neurotoxic effects of e-liquid components

Individuals with higher polygenic risk had a greater dementia risk indicative of the polygenic architecture of dementia 14

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In addition, reductions in systolic function [94], ejection fraction [95], increased systemic arterial resistance [96], as well as structural abnormalities [95, 96] have all been observed in rodent models exposed to aerosol with nicotine

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