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Studies have shown drinking too much, either in a single instance or consistently over time, can severely harm the brain, heart, liver, or pancreas, and can lead to several forms of cancer

Individual mental health factors also play an important role

Environ Health Perspect 118(6):776782

Cardiovascular effects - Nicotine is a stimulant that behaves in a similar way to caffeine

In an emailed statement to NPR, the company said "Reynolds believes these products meet and comply with all applicable regulatory requirements

1b), whereas the age effect on smoking is nonlinear, with peak rates observed in young adulthood (Fig