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Shortly after they started working together, Aki and Himeno found themselves looking off of a dark balcony and gazing moodily at the shadowy city below

Looking specifically at studies which took into account a range of factors such as age, BMI, cholesterol and blood pressure, the team found that men smoking one cigarette a day have a 74% increased risk of coronary heart disease compared with never-smokers, while women who smoked one a day had a 119% increased risk

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''More research needs to be done in order to really get a firm grasp on what the pathophysiology is behind this,'' she added

Arch Gen Psychiatry (2012) 69:77686

& Barnoya, J