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I was forced to sub-edit some copy that included a line from a tobacco company describing smoking as the last act of rebellion for the bohemian

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Long-term hypertension, diastolic dysfunction, increased cardiac after-load, myocardial fibrosis, alterations in coronary flow reserve, and ultimately left ventricular hypertrophy can result from endothelial failure besides vasoconstrictors up-regulation passageways (183)

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