glp-1 agonist mechanism Receptor Agonists as Treatments for Type 2 Diabetes GLP-1: Actions on Beta-cell Mass
Description
[PubMed] [PMC]35

Pisano as senior author

Dual GLP-1/GIP receptor agonists, such as tirzepatide, simultaneously activate both receptors, thereby potentiating glycemic control, promoting weight loss, and ameliorating metabolic dysfunction

Choosing between a pill and a shot often comes down to lifestyle, needle comfort, travel needs, cost considerations, and the ability to take the medication consistently
Another study also suggested that AgRP neurons within the ARC inhibit the WAT browning effect34)

Orlistat is a lipase inhibitor
