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Necrotic cell death is pro-inflammatory 9 and exposure of bronchial epithelial cell lines to cigarette smoke extract (CSE) induced histologic cell death suggestive of necrosis 10

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A review and meta-analysis of 20 studies published in 2011 found a strong, dose-dependent association between exposure to SHS and risk of stroke

Past 6-month individuals reporting e-cigarette use indicated the three flavors they most often use, e.g

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