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In a rat Alzheimers model induced by chloroindoleamine (CHL), Y maze and radial arm maze tests confirmed that nicotine significantly improved the spatial memory deficit, and restored the antioxidant capacity of superoxide dismutase in the rat hippocampus, showing potential properties for memory improvement ( Nicotine also plays a neuroprotective role in several animal models with Parkinsons disease

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[DOI] [PubMed] [Google Scholar] Kolattukudy, P.E