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Industrial methods, such as chemical extraction, can reduce nicotine content in tobacco leaves to very low levels, but they also have adverse effects, such as the decrease of aroma components [11]

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This review also covers some of the global regulatory policies including their challenges and loopholes

Fiction On PMIs heated tobacco products: by undermining successful tobacco control initiatives (which have denormalized smoking in many countries) by portraying this form of tobacco use as a socially acceptable Fact On the contrary, smoke-free products complement tobacco control initiatives

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