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As the disease progresses, patients may develop worsening dyspnea, recurrent exacerbations, and complications such as pulmonary hypertension and right-sided heart failure

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Similarly, the prevalence of BV is higher in patients who do not change their underpants frequently compared to those who change it more frequently (57.6% versus 36.9%) (Nelson et al., 2018), certain contraceptive methods like disposable intra-uterine devices (Marrazzo and Hillier, 2013) may also enhance the risk of developing BV

No smoking laws do prohibit smoking in public places, but these do not cover electronic cigarette use

Even many physicians smoked

[85] Likewise, multiple reviews of internal tobacco company documents have found that flavored cigarettes are deliberately introduced to appeal to young people, with flavorings often being fine-tuned to best appeal to youth