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As of yet, though, little evidence exists to support this theory

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Nicotine, a well-known component of cigarette smoke, also alter metabolic pathways particularly by interfering with Organic Cation Transporters (OCTs) in vitro (Urakami et al., 1998

Reasons for engaging in DIY practices among adolescent e-cigarette users include: the ability to increase nicotine concentrations above what is available commercially, lower costs, personal oversight of quality control, and the creative outlet provided through design and construction [24]