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In our study, female sex was again identified as a risk factor for IBS in smokers

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As several of these metabolites affect appetite and/or modulate nAChRs, the reciprocal interaction of nicotinic and lipid-signaling pathways may constitute an important feedback (pun intended) mechanism for regulating peripheral signals and circuits controlling food intake (e.g., Vijayaraghavan et al., 1995

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1 2 "$15 billion startup Juul used 'relaxation, freedom, and sex appeal' to market its creme-brulee-flavored e-cigs on Twitter and Instagram but its success has come at a big cost"