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More recently, TP53 missense mutations were identified in BCC samples, including hotspot positions p.H179Y, p.S241F, p.G245N, and p.R280K, clustering in p53 DBD [100]

Cigarettes: Anatomy of an Industry from Seed to Smoke (2002) online Porter, Patrick G

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We are at a point where 480,000 people a year die from tobacco use, Rouvelas said, referencing data from the US Centers for Disease Control and Prevention

The shorter telomere of the smokers chromosome reflects premature aging of about 5 years, and increases the risk of cancer

Atlanta, GA: US Department of Health and Human Services, Public Health Service