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That persistent smoke exposure can directly lead to acquired cisplatin resistance is shown here directly as is the cross-resistance of cisplatin resistant cells to the oxidative stress generated by cigarette smoke

Correspondingly, histomorphological abnormalities and decreased sperm numbers were observed in the testes of experimental mice (83)

To date, it is generally believed that smoking is one of the key factors in the development of COPD, but its pathogenesis has not been fully clarified

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A hidden epidemic of intermediate risk oropharynx cancer

(134) revealed no association between the TP53 polymorphism in codon 72 and male idiopathic infertility