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In recent years, synthetic nicotine products have gained a strong foothold in the local liquid e-cigarettes market, accounting for 92.2 percent of all liquid e-cigarettes in 2022, up from 76 percent in 2020, according to the Korea Health Promotion Institute

It is accompanied by increased production of reactive oxygen species (ROS) that are proposed to signal cell death, although both the origin and the precise role of ROS in the execution of this developmental program are still poorly understood

For other combustible tobacco products, current use was defined as any use of cigars, pipe and hookah tobacco in the past 30 days
It also weakens the immune system, disturbs reproductive health and affects the health of cells in the human body, which can lead to cancer

Additional research, they suggest, could focus on the amount of tobacco-related compounds that young kids ingest when they live with someone who uses smokeless tobacco, and the resulting health risks
