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Other living with human immune deficiency virus (HIV) being more than 50 years old being a smoker practicing sex without a condom or barrier method having a history of other types of cancer, especially cervical, vulvar, or vaginal having anal warts having a weakened immune system taking medications that suppress your immune system Colon cancer The exact cause of colon cancer hasnt been pinpointed, but there are a number of things that have been linked to this type of cancer