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They must continue to consume nicotine to feel normal and avoid the psychological discomfort of withdrawal

People may quit with or without the use of medications.

when it is firmly requested, meticulous planning and communication to the patient of the low rate of success of this approach are mandatory

a regular cigarette group (RC)

It has been reported that 66% of all heroin addicts have experienced a life-threatening overdose at some point, and 34% have attempted suicide

Ethics approval : All waves of the study have received ethical approval from the relevant institutional review or research ethics committee at The Cancer Council Victoria (Australia), Roswell Park Cancer Institute (USA), University of Waterloo (Canada) and University of Strathclyde (UK)