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A single puff of tobacco smoke contains more than 4000 chemicals Most of these chemicals prevent the body from functioning the way it should Between 43-80 these chemicals cause cancer In the United States, more than 400,000 people die each year because of smoke-related illnesses

Conducting additional experiments with RPE cells donated by two people without age-related macular degeneration, or AMD, who did not smoke, one person without AMD who smoked, and one person with early AMD, the researchers identified 1,698 genes that either increased or decreased in expression and were shared between dysfunctional human and mouse RPE cells

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(Brelands excitement over the results is tempered, however, as it was only an 18% quit rate for people who used e-cigarettes in the trial and received intensive counseling, compared with 9% using gums and patches.) Meanwhile, the explosion of e-cigarettes in the US, which has mostly been led by Juul, was largely due to its early marketing and advertising efforts that made using the e-cigarettes look cool