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While some reviews emphasize the role of nicotine, other systematic reviews have shown that it is complicated to assign blame solely to nicotine (64, 66, 67)

And if you want to understand whether vaping is a realistic long-term alternative to smoking, this article on vaping to quit smoking is worth your time

Nicotine shots are regulated! This is true, however, they are subject to a different set of regulations - the GPSR (General Product Safety Regulations) which assumes they will be used as intended