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Sensitivity analysis showed that exclusion of any single study did not materially alter the overall combined effect

5 Metabolism of Nicotine 5.1 Pathways of Nicotine and Cotinine Metabolism Nicotine is extensively metabolized to a number of metabolites (Fig

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The cigar or tobacco wholesaler will also likely be required to pay tax on the products it distributes and be subject to audit and a slew of other regulatory issues