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10.1038/s41467-024-52258-w 63 RakipovskiG.RolinB.NhrJ.KleweI.FrederiksenK

MS-based proteomics Pooled plasma (500 l) from the in vivo degradation study [injection of 800 fmol GLP-1(936)NH 2 ] was purified and analysed in technical triplicates using a validated platform for the detection of low-abundant peptides, as previously described [20]

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These effects are mediated through multiple mechanisms, such as weight loss, anti-inflammatory, anti-catabolic, anti-apoptotic, regulation of ROS, and autophagy, demonstrating a comprehensive protective effect on KOA (Table 3)
