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However, recent systemic reviews and meta-analyses have not shown worse outcomes

Non-parametric statistical tests for repeated measures ordinal data (Friedman test) were conducted to compare the four condition (6F, 18F, 6A, 18A) (3 degrees of freedom) to detect whether the number of people for whom an increase or decrease was shown between conditions was statistically significant for aerosol yield, nicotine, formaldehyde and acetaldehyde (as potential carcinogens)

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Specifically, PS has been shown to diminish the disease resistance of plants by downregulating disease-resistance genes 23,167

"WHO | WHO Framework Convention on Tobacco Control"

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