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A one finger, dense, deep tan colored head on the initial pour

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The linear regression correlation coefficient ( R 2 ) was greater than 0.9959 for all analytes, and the limit of detection (LOD) was determined for nicotine, NNK, and NNN at 1 ng/mL 0.005 ng/mL, and 0.006 ng/ mL, respectively

Clinically, it presents as a solitary, oval or round, erythematous plaque with a fine, trailing edge of scale, often referred to as a collarette. This lesion is commonly found on the trunk or proximal limbs and precedes the generalized eruption by several days to 2 weeks [4, 5]