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In iPSC-EC exposed to e-liquids, evidence of endothelial dysfunction were observed including lower cell viability, higher production of IL-1 and 6, ROS production, activation of OS-related pathway, caspase 3/7 activity, low-density lipoprotein uptake (LDL), and disrupted tube formation and migration [31]

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By comparison, nicotine treatment had a smaller effect on lesion areas in ApoE / mice fed with ND

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