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AzzopardiDHaswellLEFrosinaJMcEwanMGaleNThissenJet alAssessment of biomarkers of exposure and potential harm, and physiological and subjective health measures in exclusive users of nicotine pouches and current, former and never smokers

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Nicotine absolutely has hormonal effects

The observed effects are noted to be partly independent of nicotine content and nicotine may even serve to moderate the effects of non-nicotinic components on the blood-brain barrier

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