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Nicotine increases the expression of kidney injury molecule-1, the classic epithelial-mesenchymal transition (EMT) markers, vimentin, fibronectin, and production of -smooth muscle actin (-SMA), TGF-, MCP-1, and ROS in the renal epithelium
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Drinking alcohol and smoking also play a factor

While the link is not as strong as for other cancers, some environmental and occupational exposures have been investigated as potential risk factors for salivary gland cancer
You Might Be Peeing More Because spironolactone is a water pill, it can make you go to the bathroom more often

Vitamin B12: Smoking reduces vitamin B12 levels in the body
