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For people with metabolic syndrome or multiple cardiovascular risk factors, this broader metabolic improvement is potentially more important than the weight loss itself

Conclusions Tirzepatide may be a promising investigational adjunct in selected adults with T1D and overweight or obesity, particularly for weight reduction

In the most recent published trial, about 10% of people taking tirzepatide dropped out of the study because of such problems, compared with about 2% of people taking dummy shots

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That is significant, even at the lowest therapeutic dose