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These influences make individuals more susceptible to developing nicotine dependence, through repeated exposure or by interacting with other substance use behaviors

For example, a person might also be considered having a 30 pack-year history if they smoked two packs a day for 15 years

L., Cairns, B

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This can result in a temporary reduction in systemic inflammation, offering short-term relief for symptoms like brain fog, low energy, or mood instability that are common in CIRS patients

Psychopharmacology (Berl.) 1989;97:539547
