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The complainants made a large number of intellectual property-related claims, of which the one the panel most extensively discussed was the claim that plain packaging breached article 20 of TRIPS, explains a paper by the McCabe Centre for Law and Cancer

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21 Considering that these authors used an acute exposure model and the fact that nicotine makes the difference in their effects, it is possible that nicotine-containing e-cigarettes have further, previously unknown and more adverse endothelial effects than expected