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A review of 19 lung cancer studies conducted by Case Western Reserve University failed to demonstrate significant associations between marijuana smoking and lung cancer after adjusting for tobacco use. A 2018 review from Imperial College London states that: There is currently no clear association between cannabis smoking and lung cancer, although the research is currently limited

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PA can be further oxidized by xanthine oxidase (XO) to form 5-hydroxy-pyrazinoic acid (5-OH-PA), a metabolite thought to be more hepatotoxic than PA

Its a volatile organic compound found in car exhaust

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