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The study will summarise the information available to date and collect quantitative and qualitative primary data to provide a holistic view of those products and their consumers 219 Scientific inputs into policymaking are often quite cautious and liberally sprinkled with caveat

3 It is of increasing importance for clinicians to have an awareness of such products and their possible implications on oral and general health

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Centers for Disease Control & Prevention

Altria, a company that owns tobacco brands including Marlboro, spent $17 million opposing Amendment 72 in 2016

PRISMA flow diagrams describing the selection process of the studies identified in the literature searches are provided in Additional file 1: Appendix 5b,c