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In Japan, smokers tend to be more affluent, while U.S

Smoking increases the likelihood of pregnancy-related complications such as placental problems, premature rupture of membranes, and even miscarriage

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"Information about the specific product used (including brand name), whether it was modified in any way or if other tobacco products, medications, supplements or other substances were used, as well as details about product use preceding the adverse event are critical pieces of information to help fully assess this issue more broadly," said the agency's statement

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