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Recently, cigarette smoke has been shown to increase TLR3-stimulated MUC5AC production in airway epithelial cells, mainly via extracellular signal-regulated kinases (ERK)-signaling [133]
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Niemi et al., 2003)
Bibcode:2017PNAS..114.6752L
It is even more extreme for ozone, present in small amount in urban air pollution but basically absent from tobacco smoke
