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INTRODUCTION Of all modifiable behaviors, smoking has the greatest impact on death from non-communicable diseases (NCDs) 1

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Comparison of viral composition We compared viral composition across different locations using PCA, accounting for the compositional nature of metagenomic data

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Taxonomic characterization of the GM Rapidly expanding research on the influence of environmental factors on the composition of the gastrointestinal bacterial community has been conducted to evaluate potential links with human diseases and pathologies (Allais et al., Reference Allais, Kerckhof, Verschuere, Bracke, De Smet, Laukens, Van den Abbeele, De Vos, Boon, Brusselle and Cuvelier2016)