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Prenatal cigarette smoke exposure sensitizes acetaminophen-induced liver injury by modulating mir-34a-5p in male offspring mice

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Importantly, although individual mutations and their associated GOF effects can result in variable therapeutic vulnerabilities, the restoration of WT p53 function exerts comparable effects across tumours with different mutant p53 in lung cancer mouse models that can be switched from mutant p53 to WT p53 [217]

doi: 10.1242/dev.200205 35 BeumerTLRoepers-GajadienHLGademanISvan BuulPPGil-GomezGRutgersDHet al