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Protective effects were also reported in NMSC for compounds such as curcumin [116], caffeine [117], glycyrrhizic acid [118], and the -blocker carvedilol [119], by targeting p53-mediated signaling pathways

Here, the major cellular processes that can be induced by p53 and how they contribute to tumour suppression will be discussed individually

ACR, MVK and CPO are unsaturated carbonyl compounds that cause DNA damage and depletion of glutathione, an endogenous ROS scavenger [5]

HCC has a strong male preponderance, with a male-to-female ratio estimated to be 22.5:1 3

Cheung EC, Athineos D, Lee P, Ridgway RA, Lambie W, Nixon C, et al

Sun YV, Smith AK, Conneely KN, Chang Q, Li W, Lazarus A, et al
