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Gradual dose titration significantly reduces the incidence and severity of gastrointestinal symptoms
GLP-1 RAs are known to help decrease body weight, in part due to decrease in appetite, Aroda told us

Unlike Ozempic, liraglutide is officially indicated in Australia for use in weight loss

The remarkable weight loss and glucose-lowering results achieved by the dual peptides paved the way for triple GIP/GLP-1/glucagon receptor triagonists with the hope that the new combinatorial approaches provide further synergistic metabolic effects
Some patients explore gradual weaning protocols rather than abrupt discontinuation to minimize rebound