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Acrolein (ACR), methyl vinyl ketone (MVK), and 2-cyclopenten-1-one (CPO) were used in the experiments, as these are the major cytotoxic factors in CSE in various cell types
Osman AA, Arslan E, Bartels M, Michikawa C, Lindemann A, Tomczak K, Yu W, Sandulache V, Ma W, Shen L, et al

Covalent modification of the homeodomain-interacting protein kinase 2 (HIPK2) by the ubiquitin-like protein SUMO-1

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Alternatively, increasing parthanatos activation to remove cells with significant smoke induced DNA damage could prevent incorporation of genetic mutations, but lead to increased inflammation

Although most studies have supported the function of p53 in promoting ferroptosis