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THC pharmacodynamics: Modulation of multiple targets THC modulates that activity of multiple G protein-coupled receptors ( GPCRs ) and ion channels as shown by cell culture studies, and most of these targets mediate THCs bioactivity in vivo as demonstrated by fully blocking THCs bioactivity in rodent model systems using genetic deletion and/or antagonism
These mass concentrations agree with total particulate matter (TPM) measurements of fresh smoke collected on a filter directly downstream of the cigarette or joint (without dilution or aging due to sampling), which show smoking a marijuana joint produces roughly 3.4 (0.6) times more TPM than a tobacco cigarette following the same HCI routine with six puffs
Fong said it is important that people know the risks as well as the benefits when it comes to cannabis
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Yemaneberhan H, Flohr C, Lewis SA, Bekele Z, Parry E, et al
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