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Cancer Cases: Men vs Women Figure 2: Hospital Admissions for Cancer in the UK

Beyond specific CpG alterations, paternal smoking has been shown to influence the sperm epigenome, a collective term describing the set of epigenetic modifications, including DNA methylation, histone modifications and the activity of non-coding RNAs such as miRNAs, that regulate gene expression without altering the DNA sequence (9,10)

Researchers recruited 1,941 regular cigarette smokers and 3,758 menthol smokers to compare each group's overall health condition over the course of 18 months

To conclude, genetic factors play a significant role in determining ones susceptibility to nicotine addiction
