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Nicotine side effects on the skin not only lead to increased keratinocytosis but also modify the cell structure over the long term

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[14] These vasoactive amines such as histamine, heparin and serotonin released from the mast cell granules cause vasodilation, increased vascular permeability, smooth muscle contraction and increased mucus secretion

However, multivariable logistic regression analysis revealed that, although differences in semen parameters and live birth outcomes were observed between cigarette types, key predictors of live birth, such as follicle-stimulating hormone (FSH) levels and the number of two-pronuclear (2PN) embryos, did not differ significantly between the groups

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