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The Western Journal of Medicine 158 , 635 (1993)

By 2021, disposables were the most popular type of e-cigarettes, with Puff Bar emerging as the most popular brand

A key provocative, or even radical question is raised: Can the combination of technological advances (ANDS) and regulation align makers of nicotine-containing products with public health advocates to eliminate combusted tobacco as a defective and unacceptable product for human use

Think about The Walking Dead

Switching completely (not dual use) provides the most benefit

Re-thinking Nicotine: A Three-Dimensional Framework for Harm Minimization Nicotine and tobacco products can fit into a three-dimensional conceptual space (Figure 2): (1) harmfulness (x-axis), (2) appeal (z-axis) and (3) dependence (y-axis)