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Methyl Ethyl Ketone (MEK) depresses the human nervous system, irritates the eyes, nose and throat

3 Nicotine pharmacology and cardiovascular effects 3.1 Mechanisms of nicotine action As detailed by Benowitz (22) in his comprehensive review of nicotine pharmacology, nicotines addictive potential stems from its complex interaction with the nervous system, involving rapid central nervous system penetration and subsequent activation of neural reward pathways

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doi: 10.1513/AnnalsATS.201611-861OC

These toxic substances are then filtered by the kidneys and become concentrated in the urine, which exposes the lining of the bladderthe urotheliumto prolonged contact with these harmful agents

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