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Once in the brain, nicotine binds to receptors that release neurotransmitters, particularly dopaminea chemical that triggers feelings of pleasure and reward
Some people may not like it because it has a strong medicinal taste
The brain uses them to coordinate the activities of many other kinds of receptors, acting to fine tune the sensitivity of a wide variety of behaviors
By comparison to this, a single cigarette contains between 8 and 20 mg of nicotine
Psychopharmacology (Berl) 158 : 343359
