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never-smokers) Larynx cancer: RR 6.98 Oral cavity/esophagus cancer: RR 3.433.57 Bladder cancer: RR 2.58 (all smokers), 3.47 (current) Kidney cancer: RR 1.31 Pancreatic cancer: RR 1.371.49 Stomach cancer: RR 1.53 (current), 1.30 (former smokers) Colorectal cancer: RR 1.141.17 Breast cancer: RR 1.141.24 (especially with early smoking initiation) Smoking causes DNA mutations and epigenetic changes that lead to cancer

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