health risks of smoking cigarettes Smoking's Disease Burden: Worse than Previously Thought? Consequences of Smoking

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Note that participants in the previously published pilot study (14) are included in this manuscript due to the fact that the present analysis includes additional metabolites and comparison of all outcomes across product formulations

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the cigarettes are also flue-cured, meaning processed with heat to secure the sugars, which synthetically lowers the cigarette smokes pH and makes it easier to inhale

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