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51 Source: Prepared by CRS using data from the FDA, as of August 2, 2019

The settlers were becoming acclimated, and they 12 were learning the ways of the new country

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Nicotine worsens the signs and symptoms of inflammation in CD patients by triggering the Th1 and Th17 cells, which in turn raises the levels of pro-inflammatory cytokines such as TNF-, interferon-gamma (IFN-), IL-23, IL-6, and IL-1 [54]