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The film follows Dolly Parton, Lily Tomlin, and Jane Fonda as a trio of office workers who find themselves belittled and harassed by their misogynist boss

Results from mRNA expression of CD45, CD3, CD8, and CD68 showed no significant changes across TLR mutant mice, the only significant change was Ly6G which displayed a significant decrease in TLR2KO ( Supplementary Figure S3A-E )