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Densities in this range are substantially higher than the average density of the nonstripped smoke particles (990 94 kg m 3 ), and are common for many higher-molecular weight organics 41
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Due to the structural similarity of beta-lactams with the terminal D-Ala-D-Ala of the pentapeptide precursor, which is the natural substrate of PBPs, these antibiotics form a stable acyl-enzyme covalent bond with PBPs abolishing their peptidoglycan cross-linking activity (Sauvage et al., 2008)

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